Mamastrovirus


Mamastrovirus is a genus of viruses, in the family Astroviridae. Human, mammals, and vertebrates serve as natural hosts. There are currently 19 species in this genus including the type species Mamastrovirus 1. Diseases associated with this genus include: infantile gastroenteritis.

Taxonomy

Group: ssRNA

Structure

Viruses in Mamastrovirus are non-enveloped, with icosahedral and Spherical geometries, and T=3 symmetry. The diameter is around 35 nm. Genomes are linear and non-segmented, around 6.8-7kb in length.
GenusStructureSymmetryCapsidGenomic arrangementGenomic segmentation
MamastrovirusIcosahedralT=3Non-envelopedLinearMonopartite

Life cycle

Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment to host receptors, which mediates endocytosis. Replication follows the positive stranded RNA virus replication model. Positive stranded rna virus transcription, using an unknown model of subgenomic rna transcription is the method of transcription. Translation takes place by -1 ribosomal frameshifting. Human, mammals, and vertebrates serve as the natural host. Transmission routes are fecal-oral.
GenusHost detailsTissue tropismEntry detailsRelease detailsReplication siteAssembly siteTransmission
MamastrovirusHumans; mammalsEnterocytesCell receptor endocytosisBuddingCytoplasmCytoplasmOral-fecal