Mosher's debut albumEverything You Need was released in 2009 on Red Parlor Records. It was made up entirely of originals that she wrote or co-wrote, other than a cover of "Blue, Red, and Grey" by Pete Townshend. In 2010, she released her follow-up, the five-song EP City of Clowns, on Red Parlor Records. It includes a cover of Bruce Springsteen's "State Trooper". The EP was recorded in Bronxville, New York, and Encino, California. Mosher performed "Lay Me Down" on The Late Late Show with Craig Ferguson in 2009. Her song "Walk On", which she co-wrote, was featured on the soundtrack to the 2014 film Walk of Shame, starring Elizabeth Banks. She has won several Los Angeles Music Awards, including the 2005 Female Singer/Songwriter of the Year, 2006 Rock Single of the Year for her song “Mr. Madness”, and 2010 National Touring Artist of the Year.
In 2012, Mosher and fellow Los Angeles-based singer-songwriters Kristen Proffit and Jaime Wyatt formed CALICO the band, a California country Americana group, influenced by artists like Gram Parsons and Emmylou Harris, and inspired by 1960s and 1970s Laurel Canyon country-rock music. In April 2014, Wyatt was replaced by Aubrey Richmond, who joined the band on vocals, violin and mandolin, with CALICO featuring the three-part harmonies of Mosher, Proffit and Richmond. The band's first album, Rancho California, was released on September 2, 2014, on their label California Country Records, which Mosher co-founded. It features original compositions, along with a cover of Bob Dylan's "You Ain't Goin' Nowhere", and production by Rami Jaffee of the Foo Fighters. American Songwriter called the album "music of great passion and beauty, cloaked in warm acoustics and close harmonies." It won Americana Album of the Year at the 2014 Los Angeles Music Awards. Now a duo of Mosher and Proffit, their follow-up, Under Blue Skies, was released in 2017, with songs by Mosher and Proffit, plus covers of John Phillips' "California Dreamin'" and Joni Mitchell's "Ladies of the Canyon". No Depression called the album "one of the ten best Americana albums of 2017." The band performed at the 2014 Stagecoach Festival in Indio, California, and has toured the United States, United Kingdom, and Europe.
