A Criollo, Padilla was born in Chipirina, Upper Peru in 1774, the son of a local landowner. He spent the early years of his life near his hometown, joining the army at an early age. He participated in the enforcement and execution of Damaso Katari, Tupac Amaru's successor in La Paz. Though studying to be a lawyer at the University of Saint Francis Xavier, Padilla left school to marry Juana Azurduy in 1805. Her father was Spanish and her mother was Chola.
Career
Padilla joined revolutionaries in the War of Independence on May 25, 1809, the day of the Chuquisaca Revolution and briefly fled to hide in the Amerindian villages of the highlands. In 1810, when the city ofCochabamba refrained from recognizing the May Revolution, Padilla was named civil and military commander of a wide area between Chuquisaca, Cochabamba and Santa Cruz de la Sierra, It was referred to as the Republiqueta de La Laguna. From the town of Padilla, he was supported by 2,000 Indian guerrillas from Esteban Arce Province. Padilla was highly esteemed by General Manuel Belgrano and by Esteban Arze who conferred the title of Commandante upon Padilla. His wife was later honored by Belgrano for her bravery in 1816. Although he won a victory in the town of Pintatora, he was defeated in Tacobamba. He retired to the south and joined the exodus from Jujuy under the orders of Belgrano. He participated in the battles of Tucuman and Salta. He returned to Upper Peru in mid-1813 and brought together a large contingent of nearly ten thousand men. This group of rebellious Indians who supported Bartolomé Mitre were part of the Republic of La Laguna. Belgrano used them as guides and for the transportation of guns across the mountains. Padilla began an effective guerrilla war against the royalists in Mojotoro, Yamparáez, Tarabuco, Tomin, La Laguna, and a neighboring village of Azurduy. Other leaders, such as Ignacio Warnes, Juan Antonio Álvarez de Arenales and Vicente Camargo, also organized guerrilla resistance. After several weeks of fighting, the enemy seized the four children of Padilla and killed the two boys. Then the girls were used as bait to catch the Padillas. The response of Padilla and his wife, followed by some soldiers, was furious, blindly attacking their enemies to kill them. Though initially rescued, the girls died days later. From that time, he became one of the most violent leaders of Upper Peru. During the third expedition to Upper Peru, he took the city of Chuquisaca. After a series of minor battles, his forces were surrounded. Padilla was killed by the royalist Colonel Francisco Javier Aguilera in El Villar, Upper Peru, at the Battle of La Laguna while defending his homeland after being pierced by a saber. Padilla was subsequently beheaded. Padilla and his wife had five children, only the youngest of whom, a daughter, survived the War of Independence.
