Mathai

• John Mathai, economist who served as India's first Railway Minister and subsequently as India's Finance Minister
• Mathai, Sharon Mathai, an Indian-American musician who was a contestant on season two of the American version of The Voice.
• Mathai Joseph, Indian computer scientist
• Mathai Manjooran, Indian freedom fighter from Kerala
• Mathai Varghese, mathematician and an Australian Research Council Senior Research Fellow at the University of Adelaide
• M.O. Mathai, Special assistant of the Prime Minister of India Jawaharlal Nehru and author of two books
• Wanjira Mathai, Kenyan environmentalist