Konadu began his youth career with Nkoranza Republic and Upper West Republic in Ghana. He began his professional career with the legendary Kumasi Asante Kotoko FC, with whom he won the Ghana Premier League in his debut season. After brief spells playing in Tunisia and Germany, he returned to Asante Kotoko in January 1996, before moving to U.D. Leiria of the Portuguese second division in July of the following year. He would play for Leiria in the Portuguese Liga during the 1998–99 season, and then moved to rival but relegated lower division club S.C. Beira-Mar, and A.C. Marinhense. He then had a brief spell playing in Turkey, before returning to play for Ghanaian side King Faisal Babes in 2003.
Coaching career
Following his playing career, Konadu became a coach. first interning at Ghana’s Feyenoord Academy before taking on the assistant coach position of Red Bull Academy’s U-17 team in Sogakope. After participating in the 31st and 32nd International DFB coaching courses in Hennef, Germany, he received the International DFB Coaching Certificates “B” and “A” in 2008 and 2009 respectively. By then, he had moved to Ghana Premier League club All Stars F.C., leading them during the 2009–10 and 2010–11 seasons. In July 2011, Konadu was appointed as assistant coach of Asante Kotoko, the club where he first gained fame as a prolific goal scorer. He however signed on as head coach following his return from the All-Africa Games in Maputo, Mozambique, following the sacking of Serbian coach Bogdan Korak. On 3 May 2012, Konadu was appointed as the assistant coach of the Ghana national football team by the GFA, succeeding James Kwesi Appiah. On 5 June 2012, Konadu resigned as manager of Glo Premier League club Asante Kotoko after guiding the club to their 22nd league title and securing qualification to the 2013 CAF Champions League. Konadu was succeeded as manager of Asante Kotoko by, Mas-ud Didi Dramani. On 10 July 2012, Konadu was appointed as the manager of the Ghana national under-20 football team, succeeding Orlando Wellington and in January 2013, Konadu was appointed as the manager of the Ghana national under-23 football team. He was appointed caretaker manager of the men's senior national team, for the second time, in March 2017.