May began her modeling career in 2012 while a student. She also appeared on music videos, magazine cover photos and as commercial model for many advertisements. She made her acting debut with in the third season of The Sign of Love, after being selected by Forever Group, from among almost 100 amateur actresses. In 2013, she starred in her second television dramaPan Nu Thway where she played the leading role with Myat Thu Kyaw, aired on MRTV-4 in 2013, and received positive reviews for her portrayal of Pan Nu Thway, which led to increased popularity for her. She then starred in the season 2 of Pan Nu Thway, aired on MRTV-4 in 2014.
In 2014, she took on her first big-screen role in the historical filmMagical Inscription where she played the main role with Myint Myat, Tun Tun, and Shwe Hmone Yati, which premiered in Myanmar cinemas on 5 October 2018. In 2015, she portrayed the female lead in the film Moe Pann Pwint Yae Thin-Kay-Ta, alongside Han Lin Thant, which premiered in Myanmar cinemas on 14 September 2018.
2016–present: Major roles and rising popularity
In 2016, she co-starred with Sithu Win and Aung Yay Chan in the historical drama Sone See Chin Moe Tain Myar, portrayed the role of Ngwe Lamin, alongside, aired on MRTV-4 in 2017. In 2017, she gain increased attention and popularity with her role as Su Su Hlaing in the hit drama A Yake alongside Hein Htet, Net Khat, Yan Aung, Soe Myat Thuzar, Nan Sandar Hla Htun, aired on MRTV-4 in May 2018, was a huge success, topping television ratings and becoming the most watched Burmese television drama at that time. May's portrayal of the character earned praised by fans for her acting performance and character interpretation, and experienced a resurgence of popularity. The series is adapted from Ma Sandar's novel A Yake and a remake of the popular 1997 filmA Yake based on the same novel. In 2018, she starred in the historical drama Bagan Myo Thu alongside Daung and Htoo Aung, aired on MRTV-4 on 28 November 2018. The series is directed by Kyaw Thu and adapted from Mg Thein Sine's novel Bagan Myo Thu. She won the "Rising Star Award " at the 2018 Star Awards for her performance in the film Moe Pann Pwint Yae Thin-Kay-Ta. In 2019, she starred in the thriller drama seriesThe Missing Truth alongside Lu Min, Kaung Myat San, Htoo Aung, Aung Ye Htike and Naw Phaw Eh Htar, aired on MRTV-4 on 19 September 2019. In 2020, she starred in the military series Legends of Warriors with Kyaw Hsu, Aung Yay Chan, Soe Myat Thuzar which aired on MRTV-4 on 13 March 2020.