From an early Sérbulo always showed interest in the art, fifteen years old entered the Center for Arts Education in the Oaxaca City where she received initial training in various artistic disciplines such as dance, acting and visual arts. Upon completion of her studies at Oaxaca moved to Mexico City and 1987 decides to audition in the "University Center Theater " of "National Autonomous University of Mexico " where it is accepted and from that moment she began her training in the drama in June 1990 got her first film role in the film Cabeza de Vaca of Nicolas Echevarria, and September 15 of the same year, she debuted in the "University Theatre" with the play The golden altarpiece written and directed by José Sanchis Sinisterra. In 1992 she landed a small role in American film Wild Blue Moon later participated in Mexican films as Making the Fight and Bride See you where did not have much impact their characters was not until 1995 that Mayra started to emphasize in the film industry to participate in the foreign filmShadow of the Pepper Tree and from that moment her career as an actress began to take off. In 2001 she participated in the American film The Mexican where she shared credits with Julia Roberts and Brad Pitt despite the role she played in this film was not earned principal various international awards in the same year was cast as an Indian peasant in the Mexican film Y tu Mama tambien on Alfonso Cuarón. It was not until 2006 that achieved international fame by participating in the film Apocalypto directed by Mel Gibson because it was one of the main characters in this story being the most successful band that has performed in her career, this work earned her many awards and international awards as well as Apocalypto was one of the highest grossing films of 2006. In 2009 she starred in the Mexican film Spiral by Mexican filmmaker Jorge Pérez Solano where she starred as "Diamantina". Mayra has been nominated Sérbulo 4 Ariel "Best actress" now has a career spanning 20 years, participated in works of theater television and cine is one of the most recognized actresses Mexico internationally. In 2017 she started playing María in "Todos Santos", a theatre monologue written by Mónica Perea, directed by Sixto Castro Santillán, and music performed live by Ariel Torres. "Todos Santos" is the story of María, a domestic servant just about to leave to her hometown´s party. While she prepares her boss´ dinner, she tells us what made her run from her town and why she must go celebrate her departed relatives in the Day of the Death. In between honest laughter and unbearable pain and tears, "Todos Santos" talks through several important harsh facts that indigenous people live in Mexico everyday, from the entrance of drug traffic to the forced displacement of their hometowns. "Todos Santos" rapidly became a great success in Mexico City after being presented in all mayor theatres between 2017 and early 2019.