McIsaac
McIsaac is a surname. Notable people with the surname include:
- Alan McIsaac, Canadian politician
- Angus McIsaac, Canadian politician
- Billy McIsaac, Scottish musician
- Cliff McIsaac, Canadian politician
- Colin Francis McIsaac, Canadian politician
- Hazel McIsaac, Canadian politician
- Hilary McIsaac, Canadian politician
- James McIsaac, Canadian politician
- John L. McIsaac, Canadian politician
- Justin McIsaac, American wrestler
- Shona McIsaac, Scottish politician
- Tai McIsaac, Australian rugby union player
