Meconic acid


Meconic acid, also known as acidum meconicum and poppy acid, is a chemical substance found in certain plants of the poppy family, Papaveraceae, such as Papaver somniferum and Papaver bracteatum. Meconic acid constitutes about 5% of opium and can be used as an analytical marker for the presence of opium. Meconic acid has erroneously been described as a mild narcotic, but it has little or no physiological activity, and is not used medicinally. Meconic acid forms salts with alkaloids and metals. These salts as well as meconic acid esters are called meconates. Meconic acid was first isolated by Friedrich Sertürner in 1805.

Chemistry

Meconic acid is a dicarboxylic acid. Its structure contains two carboxylic acid groups and one keto group attached to a pyran ring. Meconic acid gives a red color with ferric chloride. Meconic acid is colorless and is only slightly soluble in water but readily soluble in alcohol.