2016—2017 Mekelle 70 Enderta finished second in the Ethiopian Higher League Group A after the 2016–2017 season. They earned a spot in the Ethiopian Premier League by virtue of winning a one-game playoff against Hadiya Hossana, who finished second in the Ethiopian Higher League Group. This was the club's first promotion to the top division in its history. 2017—2018 After promotion to the Ethiopian Premier League, the club officials sacked manager Getachew Dawit who helped the team earn spot in the top division. As rumoured, the main reason for the sacking of the manager was political reasons. So the club signed manager Yohannes Sahle for the 2017-2018 season. Mekelle 70 Enderta had one of their most successful campaigns in the 2017–18 season as the club was part of the title race until very late in the season before ultimately finishing 4th. After the club's first season in the top division, Mekelle 70 Enderta parted ways with head coach Yohannes Sahle. 2018—2019 On August 8, 2018, the club officially signed Gebremedhin Haile as their manager for the upcoming 2018–19 season. Manager Gebremedhin Haile, who had won his first Ethiopian Premier League title with Jimma Aba Jifar F.C. the last season. After a poor start in the Ethiopian Premier League 2018—19, highly rated manager Gebremedhin Haile helped the team break a new record in the league which was held by Saint George FC. Then after holding the record followed disappointing results, and rivals Fasil City topped the league table. The season went on as Fasil City being on top of the league with just one point ahead of Mekelle 70 Enderta until the last match of the league. July 7, 2019 was a historic day for the Red Lioness as Fasil City drop two points against Shire Endaselassie F.C. in the last match of the league and Mekelle 70 Enderta winning over Dire Dawa City with the help of Amanuel Gebremichael and Osei Mawuli goals. Then the club honored with its first Ethiopian Premier League title after tiring season. And forward Amanuel Gebremichael winning the LeagueGolden Boot scoring 18 goals.
Name and logo
The team is named after the city it was founded in, Mekelle 70 Enderta. The Club logo is a red circle, inside the circle are 2 red lions, in the middle that have Hawelti Semaetat statue, and at the top the castle of king Yohannes IV which are found in the city of Mekelle.
Grounds
The team plays its home games in Tigray International Stadium in Mekelle, Ethiopia. The stadium has a 60,000 capacity.
Derby
The club plays in the "Tigray Derby" with fellow Tigray Region club Welwalo University FC. and Fasil City which is believed to be an arch rival. The derbies enjoy relatively large attendances.
