Merck Millipore
Merck Millipore was the brand used for Merck's global life science business until 2015 when the company re-branded. It was originally formed when Merck acquired the Millipore Corporation in 2010. Merck is a supplier to the life science industry. The Millipore Corporation was founded in 1954, and listed among the S&P 500 since the early 1990s, as an international biosciences company, known widely for its micrometer pore-size filters and tests. In 2015, Merck acquired Sigma-Aldrich and merged it with Merck Millipore. In the United States and Canada, the life science business is now known as MilliporeSigma.
History
Formation and naming
In the early 1950s, Lovell Corporation won a contract from the U.S. Army Chemical Engineers to develop and manufacture membrane filtering devices and systems used to separate the molecular components of fluid samples. When the membranes were declassified in 1953 and offered for commercial use, Jack Bush, a Lovell employee, bought the company’s right to the technology for $200,000 and established the Millipore Filter Company. Bush coined the word millipore to use in the company's name to refer to large number of small openings in the microporous membrane that the company produced. At this point, however, "millipore" has become an actual word in general use apart from this company's use of it, referring to any of several filters, made from cellulose acetate membranes, capable of removing very small particles. Later the company changed its name to Millipore Corporation to reflect its growing range of products. In 2010, Merck KGaA the world's oldest chemical and pharmaceutical company- acquired Millipore Corporation to form EMD Millipore.Filters
By 1959, Millipore made porous membrane filters of cellulose esters or other materials which resembled paper in sheet form, and were brittle when dry but friable when wet. Filters consisted of nitrocellulose or polycarbonate membrane nucleopore filters ranging from pore size of 0.2 μm to 20 µm. Modern filter are Polyvinylidene fluoride and/or Polypropylene based.Growth
By 1970, Millipore had established subsidiaries in seven countries. The company opened manufacturing plants in Jaffrey, New Hampshire; Molsheim, France; Cork, Ireland; and several other locations. Millipore’s 2006 acquisition of Serologicals Corporation improved the company's position in high-growth markets such as drug discovery products and services, antibodies, cell biology reagents, and stem cell research. As of the late 2000s, Millipore was the only company providing both upstream cell culture and downstream separations offerings for biopharmaceutical production.Milestones
Here are some of the key milestones representative of Millipore’s changes and growth over the past five decades.1950s
- 1954: Jack Bush purchases the rights to a new membrane-production process developed by Lovell Chemical Company.
- 1954: Millipore Filter Corporation is officially incorporated.
- 1954: Jack Bush becomes president of Millipore. Jack is the son of Vannevar Bush, science advisor to President Roosevelt in World War II.
- 1955: Millipore receives its first patent—for microporous nylon film invented by Stanley Lovell and Jack Bush.
1960s
- 1964: Millipore establishes its first subsidiary, in France.
- 1967: Millipore introduces the Super-Q water purification system.
- 1967: Millipore establishes a subsidiary in Germany.
- 1968: Millipore establishes a subsidiary in Japan.
- 1968: Millipore introduces its Pellicon cassette product, for purifying biotherapeutics.
1970s
- 1971: Millipore introduces the original Millex syringe filter—the first disposable syringe filter.
- 1972: Millipore establishes a subsidiary in Spain.
- 1972: Millipore opens a manufacturing plant in Jaffrey, New Hampshire.
- 1973: Millipore starts manufacturing in Molsheim, France.
- 1973: Millipore introduces the Milli-Q water purification system, the world’s first lab-scale ultrapure water system.
- 1978: Millipore reaches the $100 million revenue milestone.
- 1978: Millipore opens a manufacturing plant in Danvers, Massachusetts.
- 1979: Millipore acquires Waters Associates Inc., a producer of chromatographic media and High-performance liquid chromatography instrumentation.
1980s
- 1980: Millipore introduces its low-protein binding Durapore Polyvinylidene fluoride membrane.
- 1987: Millipore is listed on the New York Stock Exchange.
- 1987: Millipore reaches the $500 million revenue milestone.
- 1988: Millipore opens a membrane manufacturing plant in Cork, Ireland.
1990s
- 1994: Millipore divests its Waters Chromatography Division and focuses on its membrane business.
- 1996: Millipore acquires the Amicon separation sciences business from W. R. Grace and Company.
- 1997: Millipore acquires Tylan General, expanding its gas purification offerings for the microelectronics industry.
- 1999: Millipore acquires Bioprocessing Limited, a developer and manufacturer of chromatography.
2000s
- 2001: Millipore spins off its Microelectronics Division, that becomes Mykrolis. It will merge with Entegris in 2005.
- 2002: Millipore opens its Biopharmaceutical Technology Center in Billerica, Massachusetts – an innovative, customer-focused facility.
- 2005: Millipore acquires MicroSafe, a European contract testing laboratory.
- 2005: Millipore acquires NovAseptic, a worldwide supplier of aseptically designed components for biotech and pharmaceutical production.
- 2005: Millipore forms an alliance with Gen-Probe to develop, manufacture and commercialize products for rapid microbiological and virus monitoring.
- 2006: Millipore acquires Newport Bio Systems, a maker of process containers and systems used in biopharmaceutical production.
- 2006: Millipore acquires Serologicals Corporation, expanding its drug discovery and development footprint.
- 2006: Millipore opens a new Research and Development Center in Bedford, Massachusetts.
- 2007: Millipore launches its new brand, signifying the company’s transformation as a Life Science leader.
- 2008: Millipore unveils a major expansion of its Drug Discovery and Development facility in St. Charles, Missouri.
- 2008: Millipore opens a new membrane casting manufacturing facility in Carrigtwohill, County Cork, Ireland.
- 2009: Millipore acquires Guava Technologies, a leading provider of bench top cell analysis systems.
- 2009: Millipore opens state-of-the-art Biomanufacturing Sciences and Training Center in Singapore.
- 2009: Millipore acquires BioAnaLab, a European-based firm specializing in the analysis of biologic drugs and vaccines.
- 2010: Merck acquires Millipore. In future, Millipore will be part of the EMD Group.
- 2015: On November 18, Merck KGaA, Darmstadt, Germany, completed a $17 billion acquisition of Sigma-Aldrich. This transaction combines EMD Millipore and Sigma-Aldrich to create a global leader in the life science industry: MilliporeSigma.
Financial history