The Mesoregion of Assis is one of the 15mesoregions of the São Paulo state, Brazil. It is located at the southwest portion of the state, and has an area of 12,710.210 km² and the seat of mesoregion is in Assis. The population of the mesoregion is 567,858 inhabitants, spread over 35 municipalities. The boundaries of Paranapanema Valley Region is Itapetininga's Mesoregion, Presidente Prudente's Mesoregion, Marília's Mesoregion and Bauru's Mesoregion, Mesoregion of Pioneer North of Paraná and Mesoregion of North Central of Paraná. The GDP is R$10.949.020,00 and the region is an important and strategic way to access the South of Brasil and Mercosul. The principal resource of Paranapanema Valley economy is Sugarcane, Agribusiness, Electronics, Software, Products chemical, Food, mechanical and others. The microregions have a huge integration with cities. Actually, Ourinhos is the most populated city in region, followed by Assis, Paraguaçu Paulista and Santa Cruz do Rio Pardo, they have populations of more than 40,000. The limits of the region with Paraná state is Paranapanema River. The region was unoccupied until the twentieth century, when the first villages were created, but only with arrival of the railroad the region developed. Over the years, the city began to receive public services like education, health, water and electricity. The main road in the region is the Raposo Tavares Highway that cuts through the middle region, connecting the state capital to the city ofPresidente Prudente. Because the connection history, especially in Microregion of Ourinhos, there is a great influence on Pioneer North of Paraná, mainly in the cities of Jacarezinho, Santo Antonio da Platina and Cambará. Meanwhile, in the Microregion of Assis, the connection with the Paraná is greatly reduced and the integration is mainly among the municipalities in the region, mainly Tarumã, Cândido Mota, Palmital and Paraguaçu Paulista. For better integration of the cities, there are as CIVAP intermunicipal arrangements and UMMES aimed at sharing common interests for development. In addition, the region is well served by secondary technical schools, colleges, institutes, universities. Highlighting the UNESP, Fatec of Ourinhos and the FEMA at Assis.
