Metro Manila Film Festival Award for Best Actress
The Metro Manila Film Festival Award for Best Actress is an award presented annually by the Metropolitan Manila Development Authority. It was first awarded at the 1st Metro Manila Film Festival ceremony, held in 1975; Charito Solis received the award for her role in Araw-Araw, Gabi-Gabi and it is given in honor of an actress who has delivered an outstanding performance in a leading role while working within the film industry. Currently, nominees and winners are determined by Executive Committees, headed by the Metropolitan Manila Development Authority Chairman and key members of the film industry.
Winners and nominees
| Key | Explanation |
| Indicates the winning actress |
1970s
1980s
1990s
2000s
2010s
2020s
Multiple awards for Best Actress
Throughout the history of Metro Manila Film Festival, there have been actresses who received multiple Awards for Best Actress. As of 2019, 7 actresses have received two or more Best Actress awards.| Actress | Record Set | First year awarded | Recent year awarded |
| Nora Aunor | 8 | 1978 | 2012 |
| Maricel Soriano | 5 | 1997 | 2013 |
| Vilma Santos | 4 | 1977 | 2004 |
| Amy Austria | 3 | 1980 | 1996 |
| Jennylyn Mercado | 2 | 2014 | 2015 |
| Gloria Romero | 2 | 2000 | 2018 |
| Judy Ann Santos | 2 | 2006 | 2019 |