Mir-BART2 microRNA precursor family
The mir-BART2 microRNA precursor found in Human herpesvirus 4 and Cercopithicine herpesvirus 15. mir-BART2 is expressed in all stages of infection but expression is significantly elevated in the lytic stage. In Epstein-Barr virus, mir-BART2 is found in the intronic regions of the BART gene whose function is unknown. mir-BART2 is thought to target the virally encoded DNA polymerase BALF5 for degradation. The mature sequence is excised from the 5' arm of the hairpin.
