Mischivirus


Mischivirus is a genus of viruses in the order Picornavirales, in the family Picornaviridae. Bats serve as natural hosts. There are currently four species in this genus, including the type species Mischivirus A.

Taxonomy

Group: ssRNA

Structure

Viruses in Mischivirus are non-enveloped, with icosahedral, spherical, and round geometries, and T=pseudo3 symmetry. The diameter is around 30 nm. Genomes are linear and non-segmented, around 8.5kb in length.
GenusStructureSymmetryCapsidGenomic arrangementGenomic segmentation
MischivirusIcosahedralPseudo T=3Non-envelopedLinearMonopartite

Life cycle

Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment of the virus to host receptors, which mediates endocytosis. Replication follows the positive stranded RNA virus replication model. Positive stranded RNA virus transcription is the method of transcription. Translation takes place by ribosomal skipping. The virus exits the host cell by lysis, and viroporins.
Bats serve as the natural host.
GenusHost detailsTissue tropismEntry detailsRelease detailsReplication siteAssembly siteTransmission
MischivirusBats-Cell receptor endocytosisLysisCytoplasmCytoplasmUnknown