Mixed tumor

True versus false

• A true mixed tumor contains multiple types of neoplastic cells. Some sources require the included tissue types to be neoplastic for the definition of mixed tumor.
• A "false" mixed tumor contains one type of neoplastic cells, but which have more than one appearance. For example, benign pleomorphic salivary gland tumors may have some tumors cells that form pseudocartilage. Yet, all the tumor cells have similar myoepithelial profile on immunohistochemistry, and are thus classified as one cell type.

Number of cell types

• A biplastic tumor or biphasic tumor consists of two tissue types.
• A teratoma is the main tumor type that often includes more than two tissue types. They may form for example hair, muscle, teeth, and/or bone.

  Examples of true mixed tumors