The Mountain Pacific Sports Federation sponsors championship competition in five men's and five women's NCAA sanctioned sports The MPSF dropped men's soccer after the 2012 season. The moves of Denver and New Mexico to other conferences left the MPSF with six soccer members, but all six would soon leave due to moves by the Western Athletic Conference. MPSF soccer member Seattle was already in the WAC, and another MPSF soccer school, CSU Bakersfield, was already committed to join the WAC in 2013. Because the WAC dropped football after the 2012 season due to a near-complete membership turnover, it needed to add another men's sport to maintain its Division I status. To that end, it invited the four remaining MPSF soccer schools to join them; all accepted, and the WAC began sponsoring men's soccer in 2013–14. In October 2015, Arizona State announced that it would elevate its club team in women's lacrosse to full varsity status starting in the 2017–18 school year, which will give the Pac-12 six women's lacrosse schools. This number is required by league bylaws for official sponsorship of a sport, and is also the number of teams required for a conference to be an automatic NCAA tournament qualifier. This led the Pac-12 to announce that all of its women's lacrosse teams would leave the MPSF for the new Pac-12 lacrosse league for the 2018 season. The four remaining MPSF lacrosse schools will retain that league's automatic NCAA tournament bid for the 2018 and 2019 seasons while the MPSF seeks to add new members in that sport. The next major change in conference membership came in January 2016, when the Golden Coast Conference, a water polo-only league that previously operated only a women's competition, announced it would add a men's division effective with the 2016–17 season. The GCC took six of the 10 members of the MPSF men's water polo league, leaving the MPSF with only the four Pac-12 members that sponsor the sport. On May 31, 2016, the Big West Conference announced that it would begin sponsoring men's volleyball in the 2017–18 school year. The Big West men's volleyball league now includes five full members Long Beach State, Cal State Northridge, UC Irvine, UC Santa Barbara and Hawai'i, plus associate member UC San Diego. The full Big West members remain in the MPSF in other sports, but UC San Diego exited the federation. California Baptist also exited the MPSF after dropping its only conference sport of men's volleyball shortly after the 2017 season, and Cal State Bakersfield left the MPSF after dropping its last remaining conference sport of women's water polo at the same time.
The Mountain Pacific Sports Federation has won 93 NCAA titles in seven sports. UCLA has won 24 national titles. Stanford has won 16 titles. USC has won 15 titles. Oregon has won 11 titles. Oklahoma has won nine titles. California has won six titles. UC Irvine has won four titles. Arizona State and Brigham Young have won three titles. Pepperdine has won two titles. The MPSF has won every men's and women's water polo NCAA title since the inception of the conference.