Mycobacterial porin


MspA porin is a membrane porin produced by mycobacteria, allowing hydrophilic nutrients to enter the bacterium. The protein forms a tightly interconnected octamer with eight-fold rotation symmetry that resembles a goblet and contains a central channel. Each protein subunit contains a beta-sandwich of immunoglobulin-like topology and a beta-ribbon arm that forms an oligomeric transmembrane beta-barrel.