Warhurst was born in Portland, Victoria in 1974. She has two older brothers named Kit and Andre. Kit plays drums in the bandRocket Science. Warhurst's family moved to Donald in central Victoria when she was a child, then to Red Cliffs in northwest Victoria when she was eight years old.
Radio
Working as a radio announcer at Triple J, Warhurst came to the attention of the station's audience through short bi-weekly segments for Merrick and Rosso's Drive program in 2000. In 2001, Warhurst began hosting the Net 50 request program on Saturday nights, and in 2003, came to prominence as host of the weekday Lunch shift and her daily segment The Trashy Lunchtime Quiz. In January 2007 she joined Jay and the Doctor in hosting The Breakfast Show as Myf, Jay and the Doctor. It was announced on 10 October 2007 that she would leave Triple J and co-host a new breakfast show with comedian Peter Helliar and take over the Triple M Melbourne breakfast spot from The Cage, who finished up in November 2007.
Television
Warhurst's television work has included hosting jtv, the December 2006 special My Favourite Album, and captaining a team on Spicks and Specks from its inception in 2005 until it finished in 2011. When finishing Spicks and Specks, Warhurst said "I've been lucky enough to experience many great things. I've seen Frank Woodley's privates, been naked under a desk with Pete Murray, and met many of my childhood musical crushes. Life can't get much better than that, so this seems like the perfect time to wind things up." Worst moments included her embarrassment at not being able to recall the name of Nirvana's "Smells Like Teen Spirit" upon hearing it. Spicks and Specks twice won the Logies' Most Outstanding Light Entertainment Program, and episodes have been repeated on ABC2 at 7.30pm on most nights. The irreverent TV Fugly Awards awarded Warhurst as their Most Spankable Female TV Personality in 2007 & 2008. Warhurst has occasionally appeared on Rove, was a special presenter on RMITV's The Loft Live and is now a regular presenter on the Roving Enterprises production, The Project. Warhurst returned to ABC1 in June 2012 with a six-part series, Myf Warhurst's Nice. In 2017, Warhurst, along with Joel Creasey, was announced as one of Australia's commentators for the Eurovision Song Contest. Warhurst appeared as a guest quiz master on Have You Been Paying Attention?. In 2018, she started voicing various characters in Bluey. In January 2020, Warhurst participated in the sixth season of the Australian version of I'm a Celebrity...Get Me Out of Here!.
