NLGN4X
Neuroligin-4, X-linked is a protein that in humans is encoded by the NLGN4X gene.
In the human brain, the synaptic protein NLGN4 is primarily expressed in the cerebral cortex.
This gene encodes a member of the neuroligin family of neuronal cell surface proteins. Neuroligins may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs, large homolog 4. Mutations in this gene have been associated with autism and Asperger syndrome. Two transcript variants encoding the same protein have been identified for this gene.
