As a true freshman, Knight averaged 8.2 points and 4.4 rebounds per game in 31 games played. Coach Tony Shaver praised his work ethic for losing 45 pounds before his sophomore season. As a sophomore, he averaged 18.5 points, 7.3 rebounds and two blocks per game and was named second team All-Colonial Athletic Association. On February 9, 2019, Knight had a career-high 39 points to go with 14 rebounds at Hofstra. He followed that up with 35 points and 13 rebounds against Elon on February 16 and 30 points in a win over College of Charleston on February 21. Knight was named first team All-CAA as a junior after averaging 21 points, 8.6 rebounds, 3.5 assists and 2.3 blocks per game. Knight became the first college basketball player since Tim Duncan at Wake Forest in 1997 to average 20 points, eight rebounds, three assists and two blocked shots per game, and his scoring average was the highest for a Tribe player since 1968. He also had 12 double-doubles. After entering the 2019 NBA draft, Knight withdrew from the draft before the deadline and decided to return to William & Mary for his senior season. Coming into his senior season, coach Shaver was fired and replaced by Dane Fischer while four players transferred, though Knight decided to stay on the team. During his senior season, Knight put up 30-point games against Buffalo and Oklahoma. On January 4, 2020, Knight hit a last-second shot in a 66–64 win against Northeastern and finished with 23 points and 11 rebounds. On February 8, 2020, Knight passed the 2,000 career point mark by scoring 16 points while also grabbing 13 rebounds. He became the fourth player in program history to reach the milestone. At the conclusion of the regular season, Knight was named CAA Player of the Year and CAA Defensive Player of the Year. He became just the second men's basketball player in CAA history to earn both awards in the same season, joining George Mason's George Evans. Knight finished the season averaging 20.7 points and 10.5 rebounds per game, the fourth CAA player to averaged 20 points and 10 rebounds in a season, and was an AP Honorable Mention All-American.
Career statistics
College
Personal life
Knight is the youngest of four children born to Joslyn McGriff. In December 2008, Knight's 18-year-old sister Yeisha Howard was stabbed to death in Syracuse. According to the prosecutor, it was part of a longstanding feud, and the perpetrator of the attack was sentenced to seven years in prison.