Neurotensin receptor
The neurotensin receptors are transmembrane receptors that bind the neurotransmitter neurotensin. Two of the receptors encoded by the and genes contain seven transmembrane helices and are G protein coupled. The third receptor has a single transmembrane domain and is encoded by the gene.Ligands
Agonists
;Peptide
;Non-peptide
Unusually for GPCRs, NTS1 can be expressed in an active form in the bacteria E. coli. It can be purified and analysed in vitro and has been analysed by a number of biophysical techniques such as surface plasmon resonance, FRET and cryo-electron microscopy.
