NY 272 begins at an intersection with NY 104 on the Orleans–Monroe county line, which also separates the towns of Clarkson and Murray. The two-lane route heads north, passing through open fields and over Sandy Creek to intersect NY 18 at Kendall Mills, a hamlet in the town of Hamlin. NY 18 briefly overlaps NY 272 northward but veers west off the county line and into Kendall south of the dual-town hamlet of Morton. The number of homes and businesses along NY 272 begins to rise during the stretch between Kendall Mills and Morton. NY 272 directly serves Morton, a small community situated equally in the town of Kendall and the town of Hamlin. In the center of Morton, NY 272 intersects Morton Road, which approaches NY 272 from the Monroe County side. North of Morton, the amount of development along the road declines sharply as it heads toward Lake Ontario. NY 272 meets the Lake Ontario State Parkway at an interchange south of the shoreline near the west end of Hamlin Beach State Park. This is the last signed highway that NY 272 intersects; however, NY 272 officially continues to the lakeside hamlet of Troutburg in the town of Hamlin, where it terminates at a dead end at the southern lakeshore. NY 272 is one of only two state highways in New York that are located wholly along a county boundary. Incidentally, the other one is NY 269 on the other side of Orleans County, which delimits the boundary between Orleans and Niagara Counties.
History
The portion of the Orleans–Monroe county line road north of Ridge Road was added to the state highway system in stages during the late 1900s and early 1910s. The section north of the Clarkson–Hamlin town line cost $39,531.05 to improve to state highway standards and was accepted into the system on December 1, 1909, as the unsignedState Highway 398. To the south, the piece between Ridge Road and the south end of SH 398 cost $20,199.14 to bring up to standards and was included in the system on November 12, 1913, as SH 588. Neither SH 398 nor SH 588 were assigned a posted designation until the 1930 renumbering of state highways in New York, when they were collectively designated as NY 272.
Major intersections
The entire route is located on the Orleans–Monroe county line.