The New York Times Non-Fiction Best Sellers of 2001
This is a list of adult non-fiction books that topped The New York Times Non-Fiction Best Seller list in 2001.
| Date | Book | Author |
| January 7 | The O'Reilly Factor | Bill O'Reilly |
| January 14 | The O'Reilly Factor | Bill O'Reilly |
| January 21 | The O'Reilly Factor | Bill O'Reilly |
| January 28 | An Hour Before Daylight | Jimmy Carter |
| February 4 | An Hour Before Daylight | Jimmy Carter |
| February 11 | An Hour Before Daylight | Jimmy Carter |
| February 18 | Ice Bound | Jerri Nielsen with Maryanne Vollers |
| February 25 | Ice Bound | Jerri Nielsen with Maryanne Vollers |
| March 4 | An Hour Before Daylight | Jimmy Carter |
| March 11 | An Hour Before Daylight | Jimmy Carter |
| March 18 | The O'Reilly Factor | Bill O'Reilly |
| March 25 | Longaberger | Dave Longaberger |
| April 1 | The O'Reilly Factor | Bill O'Reilly |
| April 8 | ' | Laura Hillenbrand |
| April 15 | ' | Laura Hillenbrand |
| April 22 | ' | Laura Hillenbrand |
| April 29 | ' | Laura Hillenbrand |
| May 6 | ' | Laura Hillenbrand |
| May 13 | ' | Laura Hillenbrand |
| May 20 | Napalm & Silly Putty | George Carlin |
| May 27 | Foley Is Good | Mick Foley |
| June 3 | Foley Is Good | Mick Foley |
| June 10 | John Adams | David McCullough |
| June 17 | John Adams | David McCullough |
| June 24 | John Adams | David McCullough |
| July 1 | John Adams | David McCullough |
| July 8 | John Adams | David McCullough |
| July 15 | John Adams | David McCullough |
| July 22 | John Adams | David McCullough |
| July 29 | John Adams | David McCullough |
| August 5 | John Adams | David McCullough |
| August 12 | John Adams | David McCullough |
| August 19 | John Adams | David McCullough |
| August 26 | John Adams | David McCullough |
| September 2 | John Adams | David McCullough |
| September 9 | The Wild Blue | Stephen Ambrose |
| September 16 | The Wild Blue | Stephen Ambrose |
| September 23 | The Wild Blue | Stephen Ambrose |
| September 30 | ' | Jack Welch with John A. Byrne |
| October 7 | ' | Jack Welch with John A. Byrne |
| October 14 | ' | Jack Welch with John A. Byrne |
| October 21 | ' | Jack Welch with John A. Byrne |
| October 28 | ' | Judith Miller, Stephen Engelberg and William Broad |
| November 4 | ' | Judith Miller, Stephen Engelberg and William Broad |
| November 11 | The No Spin Zone | Bill O'Reilly |
| November 18 | The No Spin Zone | Bill O'Reilly |
| November 25 | The No Spin Zone | Bill O'Reilly |
| December 2 | The No Spin Zone | Bill O'Reilly |
| December 9 | The No Spin Zone | Bill O'Reilly |
| December 16 | One Nation | Editors of Life Magazine |
| December 23 | The No Spin Zone | Bill O'Reilly |
| December 30 | The No Spin Zone | Bill O'Reilly |