North Carolina Highway 43 North Carolina Highway 43 is a primary state highway in the U.S. state of North Carolina. It connects many towns in the Coastal Plain region .Route description History NC 43 was established around 1928 as a new primary routing between US 17-1/NC 40, in Rocky Mount , and NC 58 , in Liberia . In 1931, NC 43 was extended southeast on new primary routing, through Pinetops , to Greenville ; then replaced NC 301 to US 17/NC 30, in Vanceboro . Around 1936, NC 43 was rerouted onto new roadway at Essex , avoiding Hollister . In 1958, NC 43 was rerouted in the downtown Greenville area, leaving behind: Charles Avenue , 10th Street , Albemarle Street and 5th Street . In 1987, NC 43 was extended south of Vanceboro along US 17 Business and US 17 to Weyerhaeuser Road. Traveling along Weyerhaeuser Road, it connects and overlap with NC 55 going into New Bern ; then with US 70 Business and southward to US 70 and US 17. The resulting new routing made a western rural bypass of New Bern. In 1998, NC 43 was rerouted onto new connector in downtown Rocky Mount. In 2001 , NC 43 was rerouted onto northern bypass route around Rocky Mount, leaving behind NC 43 Bus. In 2009, NC 43 was rerouted onto new road between NC 55 and US 17/US 70, eliminating its routing through New Bern.Major intersections Special routes North Carolina Highway 43 Business was established in 2001 , when NC 43 was rerouted to bypass north of downtown Rocky Mount. The business loop travels along Cokey Road, Fairview Road, Grand Avenue , Grace Street and Falls Road .Major intersections North Carolina Highway 43 is used by people travelling to and from Mayberry on The Andy Griffith Show . Notable episodes that reference NC 43 are "Andy's English Valet", "Man In a Hurry" and "Gomer Saves the Day".
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