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Nuclear groove
A
nuclear
groove
is an
invagination
of the
nuclear envelope
, in the
longitudinal axis
. It can be present in:
Thyroid neoplasms: It is a characteristic feature of
papillary thyroid carcinoma
, but has also been seen in other
types
of
thyroid neoplasms
, as well as in non-neoplastic thyroid
lesions
.
Ovarian tumors including
Brenner
tumors,
adult
granulosa cell tumors
, and
transitional cell
tumors.
Breast carcinomas
Vaginal,
cervical
and/or
endometrial neoplasms
Papillary
neoplasms
of several organs:
papillary transitional cell carcinoma
of the
urinary bladder
,
papillary renal cell carcinoma
,
papillary endometrioid carcinoma
of
the prostate
, in
thymic carcinomas
, and in non-epithelial tumors.