The first written mention of the village comes from 1371, the reign of emperor Charles IV, when the Moravian margraveJohn Henry passed the land of Uherský Ostroh to his son John Sobieslaus. At that time, the village was called Majori Lhota. In 1421, the so far Catholic parishioners had to follow the example of their master Hašek of Waldsheim and adopt the religion of the Moravian Brethren. In the Hussite Wars, they fought along with the Hussites. In 1511, John of Kunovice bought the land of Ostroh and his house later held it until the Thirty Years' War. At that time, the village was named Ostrovská Lhota, Ostrá Lhota or Kamenná Lhota. In 1592, the lords of Kunovice had a first register of cottars and their property made - Registra správní panství ostrovského léta 1592. This register listed a total of 72 family farms. The following names were listed there and have been preserved up to the 20th century: Blahuš, Vaněk, Vlk, Pavelka, Štajnoch, Bachan, Hanáček, Válek, Hanák, Malušek. After the Battle of White Mountain, the last lord of the land, John Bernard of Kunovice, escaped to Transylvania and his property was bought in 1625 by Gundakar of Liechtenstein, whose descendants held the village until 1918. At the change of the 16th and 17th century, the village suffered attacks by the Kuruc, Turkish and Tatar peoples from the kingdom of Hungary and was repeatedly burned down. An independent clerical ministry in the parish was founded in 1766 by countryman Jan Maluš, a priest in the nearby village of Blatnice pod Svatým Antonínkem, which the parish of Ostrožská Lhota had previously belonged to. During the Austro-Prussian War of 1866, the retreating Austrian soldiers spread an epidemic of cholera into the village, which caused a death of several dozens of its inhabitants. The present parish church dedicated to St. James the Greater was built in 1908, in place of a torn down church building from 1832, whose tower originated from the oldest known church, collapsed in 1830.
Present time
In 2007, a solar energypower plant was installed in Ostrožská Lhota, which in the time of its inauguration was the largest power plant of this kind in Central Europe, reaching an output of 702 kWp.
