PARD3
Partitioning defective 3 homolog is a protein that in humans is encoded by the PARD3 gene.Function
PARD proteins, which were first identified in C. elegans, are essential for asymmetric cell division and polarized growth, whereas CDC42 mediates the establishment of cell polarity. The CDC42 GTPase, which is controlled by nucleotide exchange factors and GTPase-activating proteins, interacts with a large set of effector proteins that typically contain a CDC42/RAC -interactive binding domain.Interactions
PARD3 has been shown to interact with:
