PREB


Prolactin regulatory element-binding protein is a protein that in humans is encoded by the PREB gene.
This gene encodes a protein that specifically binds to a Pit1-binding element of the prolactin promoter. This protein may act as a transcriptional regulator and is thought to be involved in some of the developmental abnormalities observed in patients with partial trisomy 2p. This gene overlaps the abhydrolase domain containing 1 gene on the opposite strand.