PRKCSH


Glucosidase 2 subunit beta is an enzyme that in humans is encoded by the PRKCSH gene.
This gene encodes the beta-subunit of glucosidase II, an N-linked glycan-processing enzyme in the endoplasmic reticulum. This protein is an acidic phospho-protein known to be a substrate for protein kinase C. Mutations in this gene have been associated with the autosomal dominant polycystic liver disease. Alternatively spliced transcript variants encoding distinct isoforms have been observed.