PTPRN
Receptor-type tyrosine-protein phosphatase-like N is an enzyme that in humans is encoded by the PTPRN gene.Function
The protein encoded by this gene is a member of the protein tyrosine phosphatase family and subfamily. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus.Interactions
PTPRN has been shown to interact with SPTBN4.
