Pedro de Arbués was born at Épila in the region of Zaragoza to the nobleman Antonio de Arbués and Sancia Ruiz. He studied philosophy perhaps in Huesca but later travelled to Bologna on a scholarship to the Spanish College of Saint Clement which was part of the Bologna college. He obtained his doctorate in 1473 while he served as a professor of moral philosophical studies or ethics. Upon his return to Spain he became a member of the cathedral chapter of the canons regular at La Seo where he made his religious profession in 1474. At around that time Ferdinand and Isabella had obtained from Pope Sixtus IV a papal bull to establish in their kingdom a tribunal for searching out heretics. Those Jews who had received baptism were known as conversos; some might have continued to practice Judaism in secret. Tomás de Torquemada was in 1483 appointed as the Grand Inquisitor for Castile. He then appointed Arbués and Pedro Gaspar Juglar as Inquisitors Provincial in the Kingdom of Aragon on 4 May 1484. Their work was opposed by converts and people who saw it as a threat to their freedoms. On 14 September 1485 Pedro was attacked in the cathedral as he knelt before the altar and had been wearing armour since he knew his work posed great risks. Despite wearing a helmet and chain mail he died from his wounds on 17 September. His remains were entombed in a special chapel dedicated to him. The Inquisition was opposed in Aragon as it was seen as an imperial attack on the charters, privileges and local laws. The most powerful families among the converted Jews: the Sánchez, Montesa, Paterno and Santangel families seem to have been involved in the murder. As a result, a popular movement against the Jews arose in which nine were executed, two killed themselves, thirteen were burnt in effigy, and four punished for complicity, from 30 June to 15 December 1486, according to the historian Jerónimo Zurita. Leonardo Sciascia in Morte dell'inquisitore writes that Arbués along with Juan Lopez Cisneros are "the only two cases of inquisitors who died assassinated".
Sainthood
beatified the late priest in Rome on 20 April 1664. His canonization was celebrated on 29 June 1867 among protests from Jews and Christians. Pope Pius IX said in the document formalizing the canonization : "The divine wisdom has arranged that in these sad days, when Jews help the enemies of the church with their books and money, this decree of sanctity has been brought to fulfillment".