The Pemmasani Nayaks ruled Yadiki, Gutti and Tadipatri with Gandikota as capital. The maximum extent of Pemmasanis feudatorial influence ranged from Gandikota to Kondapalli during the reign of Pemmasani Ramalinga Nayaka which includes areas like Gutti, Kurnool fort, Kondaveedu, Bellamkonda, Raichur, Kanchi, Tadipatri, Yadaki. They ruled from Gandikota as their capital. Pemmasanis ruled mostly as autonomous rulers of Gandikota. Pemmasanis helped Araveeti kings to ascend the throne of great Vijayanagar Empire when there was power shift between Tuluva and Araveedu dynasties after the Battle of Tallikota in 1565 A. D. where the Vijayanagar empire under Tuluva dynasty rule faced huge defeat against combined forces of Deccan Sultanates. Pemmasanis played a crucial role in protecting the Vijayanagar empire. This is evident from the prime location of land that Vijayanagar kings have provided to Pemmasanis in Hampi as camp when they visited the city.
The first ruler of Pemmasani clan was Pemmasani Timmanayudu who fought many a battle and won the trust of Bukka Raya. Veera Thimma had a son by name Chennappa who had two sons Ramalinga Naidu and Peda Thimma Naidu. Ramalinga ruled Gandikota during the time of Krishna Deva Raya. Ramalinga had 80,000 soldiers under him and he played a crucial role in the victory of Krishna Deva Raya over the combined armies of Kalaburagi, Golkonda and Ahmednagar. His exploits in the battle were extolled by many Telugu poets. He was the most feared by the Generals of Bijapur, Ahmednagar and Golconda. Thimma Naidu II participated in the expeditions of Krishna Deva Raya and captured Udayagiri, Addanki, Kondapalli, Rajahmundry and Katakam. He also played a crucial role in the conquest of Ummattur. After the death of Krishna Deva Raya in 1529, his son-in-law Rama Raya took control of the kingdom. The Bahamani sultan colluded with Salakam Timmaraja and raided Vijayanagar. Ramaraya took refuge in Gandikota. Bangaru Thimma Naidu vanquished Bahamanis in a fierce battle at Komali, killed Salakam Timmaraja and restored the throne to Ramaraya.
After the battle of Talikota, one section of Gandikota Pemmasani family migrated to Tamil Nadu and established Kuruvikulam Zamindari. This is the most prominent Zamindari estate in Tamil Nadu. It existed from 1565 to 1949.
