State Route 368 begins at an intersection with State Route 268 on the shores of the Allegheny River in Parker. Just after the eastern terminus, the highway crosses over the Allegheny on the Parker Bridge. The highway crosses Perryville Road on an overpass, just before intersecting at a jughandle. After Perryville Road, State Route 368 enters a small, rural region of Parker Township. At the intersection of Terwillger Road, the highway enters the community of Parkers Landing. Paralleling Perryville Road to the south, State Route 368 passes a more suburban area of Parker Township. Just after leaving Parkers Landing, Perryville Road, which had been paralleling, merges back into the state route. Hagertown Road then starts to parallel, but this also ends, with Hagertown merging in less than a half-mile later. After Hagertown Road, State Route 368 progresses straight to the northeast through a rural, undeveloped terrain. At a break in a surrounding forest, the highway begins to re-develop its surroundings, entering Perry Township. At Lime Plank Road and Doc Walker Road, State Route 368 enters the "downtown" community of Perry Township, leaving soon after for more forests. The highway continues farther, intersecting with Keefer Road. To the north, there is a large clearing, which also follows Keefer Road. At the Myers Hollow Road intersection, State Route 368 turns off its eastern progression and onto a northeastern one. There is some development along the highway, but this is uncommon. Nearing another change in direction, the area becomes more developed. After Callensburg Road, State Route 368 makes a curve to the east, entering the borough of Callensburg. Changing officials name from Route 368 to Main Street, the highway enters the downtown area. At Scott Street, the highway is well-developed. However, this changed in reverse, crossing into a small patch of forests. After the forest turns to clearing, State Route 368 terminates at an intersection with State Route 58, Craig Road and High Lane, locally maintained roads.
History
State Route 368 was assigned in the mass numbering of state highways in Pennsylvania during 1928. Also, the highway extended farther than State Route 58 to State Route 68 in Sligo. The entire highway at the time of assignment was not paved, save a couple of pieces. The highway was paved in 1930 from State Route 268 in Parker to the Perryville Road intersection. However, one piece was yet to be completed. In 1932, the section from West Freedom to Sligo was paved, completing the highway. In 1935, the highway was realigned off Perryville Road, and onto a constructed alignment. In 1967, the eastern terminus of State Route 368 was moved from its parent route to an intersection with State Route 58 in Callensburg.
