Peroxiredoxin classification index


PeroxiRedoxin classification indEX is a database of peroxiredoxins classified into one of six distinct subfamilies. Classification relies on the Deacon Active Site Profiling approach that utilizes a position specific scoring matrix created from aligned signatures to search sequence databases. Searches of PREX for Prxs of interest can be conducted using protein annotation, accession number, PDB ID, organism name, or protein sequence for Prx proteins extracted from January 2008, November 2010, or October 2011 versions of GenBank. Output includes the subfamily to which each classified Prx belongs, accession and GI numbers, genus and species, and the active site signature used for classification. The query sequence is also presented aligned with a select group of Prxs for manual evaluation and interpretation by the user. This resource is freely available to the research community.