Phenylpiperidine
Phenylpiperidine is a chemical compound with a phenyl moiety directly attached to piperidine. There are a variety of pharmacological effects associated with phenylpiperidines including morphine-like activity or other central nervous system effects.
| Compound | N | 4-position | 3-position | 4'-position | Type of pharmacology |
| MPPP | Me | Ph | H | -OCOEt | Opioid analgesic |
| Prodine | Me | Ph | Me | -OCOEt | Opioid analgesic |
| PEPAP | CH2CH2Ph | Ph | H | -OCOMe | Opioid analgesic |
| Pethidine | Me | Ph | H | -CO2Et | mu-Agonist with serotonin reuptake inhibitor properties |
| Budipine | t-Bu | Ph | H | Ph | Antiparkinson agent |
| Ketobemidone | Me | 3-HO-Ph | H | -COEt | Opioid and NMDA antagonist |
| Paroxetine | H | 4-F-Ph | -CH2OAr | H | Selective serotonin reuptake inhibitor |
| Femoxetine | Me | Ph | -CH2O | H | Selective serotonin reuptake inhibitor |
| CPCA | Me | 4-Cl-Ph | -CO2Me | H | Monoamine reuptake inhibitor |
Methylphenidate is a benzylpiperidine.