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Pho4
Pho4
is a
basic helix-loop-helix
transcription factor
found in
S. cerevisiae
and other
yeasts
.
The Pho4
homodimer
binds
to
DNA sequences
containing
the bHLH
binding site
5'-CACGTG-3'. This
sequence
is found in the
promoters
of
genes
upregulated
in
response
to
phosphate
availability
such as the PHO5
gene
.