Phosphamidon


Phosphamidon is an organophosphate insecticide first reported in 1960. It acts as a cholinesterase inhibitor.
The commercial product typically exists as a mixture of 70% -isomer and 30% -isomer.

Toxicity and regulation

Phosphamidon is very highly toxic to mammals and is listed as WHO Hazard Class Ia. A harvester developed symptoms of moderately severe poisoning after working in a field that had been sprayed with the chemical 2 weeks earlier. He collapsed and exhibited significant depression of serum cholinesterase, but recovered completely within 2 days after successful treatment with atropine. International trade of phosphamidon is covered by the Rotterdam Convention.