Phosphatidylinositol N-acetylglucosaminyltransferase
In enzymology, a phosphatidylinositol N-acetylglucosaminyltransferase is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are UDP-N-acetylglucosamine and phosphatidylinositol, whereas its two products are UDP and N-acetyl-D-glucosaminylphosphatidylinositol.
The mammalian enzyme is composed of at least six subunits. PIG-A is the catalytic subunit.
This enzyme belongs to the family of glycosyltransferases, to be specific the hexosyltransferases. The systematic name of this enzyme class is UDP-N-acetyl-D-glucosamine:1-phosphatidyl-1D-myo-inositol 6-transferase. Other names in common use include UDP-N-acetyl-D-glucosamine:phosphatidylinositol, N-acetyl-D-glucosaminyltransferase, uridine diphosphoacetylglucosamine, and alpha1,6-acetyl-D-glucosaminyltransferase. This enzyme participates in 3 metabolic pathways: glycosylphosphatidylinositol-anchor, ???, and glycan structures - biosynthesis 2.
