In pill mills, doctors or staff supervised by them prescribe opioids for non-existent or exaggerated pain. The primary purpose behind this prescribing practice is not to relieve pain or cure it, but to make high profits. This makes pill mills a criminal enterprise. Characteristics of such facilities include that they are often owned by non-medical personnel and only cash is accepted. Medical records, findings, or X-rays are not required; no medical examinations are performed or are merely pro forma; alternatives to treatment with tablets are not discussed; strong painkillers are prescribed; and prescriptions can only be redeemed at certain pharmacies. Additionally, long queues are visible in front of the facilities, parking spaces in front of or near the facility are heavily frequented, and security personnel or doormen are used. According to investigating authorities and scientists, such facilities come in different shapes and sizes, but for them it is important to give the impression that they are independent pain treatment centres. To avoid prosecution, pill mills' managers tend to run their facilities like pop-up stores. Clients of pill mills are addicted to pills or trade their pills.
Facilitated access to powerful painkillers is contributing to the opioid epidemic in the United States, as clients who take these drugs over a long period of time become accustomed to them and may need higher doses to achieve the same alleviating or pleasurable effect. In addition, the opiates in these drugs have a euphoric effect. When used regularly, the foreign opiates can replace the functions of the body's own endorphins, resulting in high addiction. Drug abuse leads to increasing numbers of cases in emergency rooms, cost-intensive treatment of addictions and frequent overdose deaths. Excessive prescription practice, negligent and absurd practice, and the promotion of drug addiction and illegal drug trafficking are violations of medical ethics and laws. For this reason, a large number of police operations, measures by the Drug Enforcement Administration and closures of these facilities have occurred. Many perpetrators were convicted by the courts, and by the end of 2016 there were 378 physicians in Florida alone, with 95 more under indictment there by that time. In response to the growing problems with narcotics abuse, a number of states have tightened their laws. In Kentucky, for example, a law to improve monitoring of prescription practices, known as the Pill Mill Bill, has been in effect since 2012. By 2012, 41 U.S. states had implemented such monitoring programs, and by 2019 all states except Missouri had implemented such programs. There is debate in the literature whether and about the extent to which the tightening of narcotics laws is causing addicts to turn to other addictive substances such as heroin, with many heroin addicts generally claiming that they have previously abused prescription opioids. Addicts also switched to fentanyl, often with fatal consequences.
Adaptations
The OxyContin Express, a 2009 documentary by Portuguese journalist Mariana van Zeller, which follows the sales channels of pill mills in Florida, received further awards and nominations for the Emmy in addition to the Peabody Award. The American television seriesAmerican Greed, which has been dealing with white-collar crime since 2007, focused on pill mills in episodes 137 and 152. Money laundering for a pill mill plays an important role in the TV seriesClaws. The documentary The Pharmacist, released on Netflix in 2020, shows how Dan Schneider uncovered a pill mill in St. Bernard Parish, Louisiana through private investigations.