Potassium ferricyanide is the chemical compound with the formula K3. This bright red salt contains the octahedrally coordinated ferricyanide|3− ion. It is soluble in water and its solution shows some green-yellow fluorescence. It was discovered in 1822 by Leopold Gmelin, and was initially used in the production of ultramarine dyes.
Like other metal cyanides, solid potassium ferricyanide has a complicated polymeric structure. The polymer consists of octahedral3− centers crosslinked with K+ ions that are bound to the CN ligands. The K+---NCFe linkages break when the solid is dissolved in water.
Applications
The compound has widespread use in blueprint drawing and in photography. Several photographic print toning processes involve the use of potassium ferricyanide. Potassium ferricyanide was used as an oxidizing agent to remove silver from color negatives and positives during processing, a process called bleaching. Because potassium ferricyanide bleaches are environmentally unfriendly, short-lived and capable of releasing hydrogen cyanide gas if mixed with acid, bleaches using ferric EDTA have been used in color processing since the 1972 introduction of the Kodak C-41 process. In color lithography, potassium ferricyanide is used to reduce the size of color dots without reducing their number, as a kind of manual color correction called dot etching. It is also used in black-and-white photography with sodium thiosulfate to reduce the density of a negative or gelatin silver print where the mixture is known as Farmer's reducer; this can help offset problems from overexposure of the negative, or brighten the highlights in the print. The compound is also used to hardeniron and steel, in electroplating, dyeing wool, as a laboratory reagent, and as a mild oxidizing agent in organic chemistry. Potassium ferricyanide is also one of two compounds present in ferroxyl indicator solution which turns blue in the presence of Fe2+ ions, and which can therefore be used to detect metal oxidation that will lead to rust. It is possible to calculate the number of moles of Fe2+ ions by using a colorimeter, because of the very intense color of Prussian blue Fe43. Potassium ferricyanide is often used in physiology experiments as a means of increasing a solution's redox potential. As such, it can oxidize reduced cytochrome c in intact isolated mitochondria. Sodium dithionite is usually used as a reducing chemical in such experiments. Potassum ferricyanide is used to determine the ferric reducing power potential of a sample. Such a measurement is used to determine of the antioxidantproperty of a sample. Potassium ferricyanide is used in many amperometric biosensors as an electron transfer agent replacing an enzyme's natural electron transfer agent such as oxygen as with the enzymeglucose oxidase. It is used as this ingredient in many commercially available blood glucose meters for use by diabetics. Potassium ferricyanide is combined with potassium hydroxide and water to formulate Murakami's etchant. This etchant is used by metallographers to provide contrast between binder and carbide phases in cemented carbides.
Prussian blue
, the deep blue pigment in blue printing, is generated by the reaction of K3 with ferrous ions as well as K4 with ferric salts. In histology, potassium ferricyanide is used to detect ferrous iron in biological tissue. Potassium ferricyanide reacts with ferrous iron in acidic solution to produce the insoluble blue pigment, commonly referred to as Turnbull's blue or Prussian blue. To detect ferric iron, potassium ferrocyanide is used instead in the Perls' Prussian blue staining method. The material formed in the Turnbull's blue reaction and the compound formed in the Prussian blue reaction are the same.
Safety
Potassium ferricyanide has low toxicity, its main hazard being that it is a mild irritant to the eyes and skin. However, under very strongly acidic conditions, highly toxic hydrogen cyanide gas is evolved, according to the equation: The reaction with hydrochloric acid is as follows:
