Prahran fields Senior, Reserves, Club XVIII and junior teams. The senior team was coached in 2006 by Leigh Stafford, who resigned from the coaching role at the end of the season. In 2007 the new coach is Paul Greenham, who has played for Richmond, Port Melbourne & St Kevins. Its sister team is the – a Division 1 Victorian Women's Football League team.
Harold Bray – finished in the top three in the Brownlow Medal three times
Andre Pitts played his 350th game for the club in 2007
Tony Free – player-coach in 2001 and 2002 after retiring from an illustrious career with the Richmond Football Club including being Captain of the Tigers.
Kevin Sheedy – former coach of Essendon Football Club and former Richmond player, began his football career with Prahran.
Sam Kekovich – North Melbourne Premiership player and well known football identity.
Don Chipp – Australian Federal politician. A former Liberal Minister in the Australian government and inaugural leader of the Australian Democrats political party. Played in the club's 1951 VFA Premiership team.
A club from Prahran first played as a senior club in the Victorian Football Association in 1886 and 1887, playing its games first at the Warehouseman's Cricket Ground, then at the Wesley College Ground. After 1887, it amalgamated with the neighbouring St Kilda Football Club, which was based less than a mile away. A new senior Prahran Football Club was established in March 1899, and joined the VFA that season, this time playing at Toorak Park, approximately two miles from St Kilda. It played in the VFA between 1899 and 1994, with the exception of 1959, when it competed in the Metropolitan League; this was because the Prahran Council would not lease Toorak Park to Prahran's Seconds team, leaving the club expelled from the Association's requirements for failing to meet its minimum home ground requirements. At the end of 1994, when administration of the VFA was turned over to the Victorian State Football League, Prahran left the Association as part of the VSFL's efforts to reduce the size of the VFA and align it with the TAC Cup; Prahran's identity was carried on within the TAC Cup from 1995, when the Central Dragons club moved to Toorak Park and was renamed the Prahran Dragons, a name it carried until the end of 1999. The club continued to exist in an administrative capacity after its departure from the VFA, and continued to operate the Prahran Tabaret – a gambling bar it owns and operates in Chapel Street, Prahran – despite having no on-field presence. In 1999, the club merged with Southbank Amateur Football Club in 1999 and joined the Victorian Amateur Football Association under the stewardship of Herald Sun racing writer Tim Habel. It also re-established its junior arm; and, after commencing with just two junior teams, the club now has eight junior teams and has formed a joint Under 19 team with Caulfield Football Club. In 2010, a joint venture with Assumption College was approved and in 2011 the club changed its name to Prahran/Assumption Football Club.
