Prosultiamine


Prosultiamine is a disulfide thiamine derivative discovered in garlic in Japan in the 1950s, and is a homolog of allithiamine. It was developed as a treatment for vitamin B1 deficiency. It has improved lipid solubility relative to thiamine and is not rate-limited by dependency on intestinal transporters for absorption, hence the reasoning for its development. It has been studied as a potential treatment for infection with human T-lymphotropic virus, since it has been shown to reduce viral load and symptoms.