Prudencio
Prudencio or Prudêncio may refer to the following people
;Given name
- Prudencio Benavides, Cuban baseball center fielder and manager
- Prudencio Cardona, Colombian boxer
- Prudencio Indurain, Spanish cyclist
- Prudencio Norales, Honduran football midfielder
- Prudencio de Orobio y Basterra, Spanish merchant, soldier and government official
- Prudencio Ortiz de Rozas, Argentine general
- Prudencio de Pena, Uruguayan basketball player
- Pruden, nickname of the Spanish footballer Prudencio Sánchez Fernández
- Prudencio de Sandoval, Spanish historian and Benedictine monk
- San Prudencio, Spanish anchorite and cleric, bishop of Tarazona
- *San Prudencio festival
;Surname