After the death of his father in 1431, Przemysław II ruled over all the Duchy together with his brothers as co-rulers, but under the tutelage of their mother. On 29 November 1442 the formal division of the Duchy took place between Bolesław I's sons: Przemysław II took over Cieszyn, Bielsko and Skoczów. Przemysław II sought to actively interfere in political affairs. In 1443 he expressed his consent to the sale of the Duchy of Siewierz to Zbigniew Oleśnicki, Bishop of Kraków, in return for which he received from Wenceslaus I the amount of 500 pieces of silver. In 1447, together with his brother Bolesław II, he participated in the Congress of Kraków, where he supported Poland in a dispute about Siewierz. In 1447, the death of his mother Euphemia finally enabled Przemysław II and his brother Bolesław II to move to their domains in Skoczów and Fryštát. Bolesław II died in 1452, leaving one son, Casimir II. Przemysław II took over the guardianship of his orphaned nephew. Przemysław II supported his suzerain, the Bohemian king George of Podebrady and also maintained close ties with the Polish kingCasimir IV Jagiellon, which was demonstrated, for example, in 1454, when Przemysław II received in Cieszyn Princess Elisabeth of Austria, on her way to Kraków for her wedding to King Casimir IV. However, the good relations with Poland deteriorated after the dispute between Poland and Duke John IV of Oświęcim, which finally ended after a further agreement on 1 July 1457 in Kraków. Three years later, Przemysław II was present at a meeting between the Kings of Poland and Bohemia in Bytom, where he served as conciliator. The next mediation took place on 9 June 1461 between John IV of Oświęcim and the King of Poland. In 1460 Władysław, another of Przemysław II's brothers, died without issue. In his will, he left his domains – half of both Głogów and Ścinawa – to his widow Margareta of Celje and Przemysław II, who actually took effective power over all the lands. Przemysław II tried to get closer to Bohemian and Polish rulers and in 1462 in Głogów both kings met and negotiated the future of the Bohemian Kingdom. As a reward for his services, he received the town of Valašské Meziříčí in eastern Moravia, only during his lifetime. In 1466 the prince took an active part in the expedition of George of Podebrady to Kłodzko, causing tension between Cieszyn and the powerful Wrocław. After the abdication of his brother Wenceslaus I in 1468, Przemysław II could take power over Cieszyn, although the former duke in fact renounced on behalf of his nephew Casimir II. In 1469 he took part in the election of Hungarian kingMatthias Corvinus as King of Bohemia in Olomouc, mainly thanks to the efforts of Pope Paul II and insurgent Bohemian Catholic nobility. For some time, Przemysław II went to Hungary and Bohemia, and even took part in the war against Corvinus' enemies in the Upper Silesia. It appeared, however, that Matthias Corvinus didn't recompense Przemysław II for his support, but also tried depriving him of Cieszyn. In this situation, in 1471 Przemysław II joined the opposition against the King, supporting the Bohemian candidacy of Prince Vladislaus II Jagiellon, son of Casimir IV. Trying to shift between Poland, Bohemia and Hungary, in 1473 Przemysław II supported Matthias Corvinus in his war against Duke Wenceslaus III of Rybnik. However, the common victory didn't improve his relations with the Hungarian monarch. In 1474 Wenceslaus I, the last surviving brother of Przemysław II, died without issue, allowing him to unify all their domains under his rule. Przemysław II's growing importance, however, didn't please Bohemian-Hungarian king Matthias Corvinus, who, during the meeting of Racibórz in 1475, obtained from Casimir IV of Poland the guarantee that he could interfere without difficulties in the sovereignty over the Duchy of Teschen, threatening to completely deprive Przemysław II if he didn't pay a huge contribution. The Duke was saved from a final fall against the Hungarian-Polish army expedition, thanks to Jakub z Dębna, who supported the defense of Cieszyn. Przemyslaw II, however, had to agree to the seizure of half of both Głogów and Ścinawa in 1476 by King Matthias. After, Przemysław II retained only the main town of Cieszyn and a few cities. He died soon afterwards, on 18 March 1477 and was buried in the Dominicanchurch in Cieszyn. Without male issue, on his death he was succeeded by his nephew Casimir II, the only male member of the Cieszyn branch.
Marriage and issue
Around 1465, Przemysław II married Anna, daughter of Duke Bolesław IV of Warsaw. They had one daughter: