Quasqueton was the location that several Native American trails intersected. It was first settled by Euro-Americans in 1842 and had a post office starting in 1845. In 1858 the Quaqueton Mutual Protection Company was organized to prevent against horse thievery. In 1904 most of Quasqueton was destroyed in a fire.
Geography
Quasqueton is located at . According to the United States Census Bureau, the city has a total area of, of which is land and is water.
As of the census of 2010, there were 554 people, 232 households, and 162 families living in the city. The population density was. There were 269 housing units at an average density of. The racial makeup of the city was 97.1% White, 0.9% African American, 0.2% Asian, 0.2% from other races, and 1.6% from two or more races. Hispanic or Latino of any race were 0.7% of the population. There were 232 households of which 24.6% had children under the age of 18 living with them, 57.8% were married couplesliving together, 7.8% had a female householder with no husband present, 4.3% had a male householder with no wife present, and 30.2% were non-families. 22.8% of all households were made up of individuals and 9.5% had someone living alone who was 65 years of age or older. The average household size was 2.39 and the average family size was 2.80. The median age in the city was 40.4 years. 20.9% of residents were under the age of 18; 9.3% were between the ages of 18 and 24; 26% were from 25 to 44; 30.7% were from 45 to 64; and 13% were 65 years of age or older. The gender makeup of the city was 51.8% male and 48.2% female.
2000 census
As of the census of 2000, there were 574 people, 227 households, and 167 families living in the city. The population density was 501.0 people per square mile. There were 254 housing units at an average density of 221.7 per square mile. The racial makeup of the city was 97.04% White, 1.39% African American, 1.05% Native American, 0.17% Asian, 0.35% from other races. Hispanic or Latino of any race were 0.87% of the population. There were 227 households, out of which 31.3% had children under the age of 18 living with them, 61.7% were married couples living together, 9.3% had a female householder with no husband present, and 26.4% were non-families. 19.4% of all households were made up of individuals, and 10.1% had someone living alone who was 65 years of age or older. The average household size was 2.53 and the average family size was 2.92. In the city, the population was spread out, with 26.1% under the age of 18, 6.3% from 18 to 24, 25.6% from 25 to 44, 26.8% from 45 to 64, and 15.2% who were 65 years of age or older. The median age was 38 years. For every 100 females, there were 104.3 males. For every 100 females age 18 and over, there were 101.9 males. The median income for a household in the city was $36,518, and the median income for a family was $45,417. Males had a median income of $28,125 versus $23,750 for females. The per capita income for the city was $15,913. About 7.9% of families and 9.9% of the population were below the poverty line, including 13.6% of those under age 18 and 6.3% of those age 65 or over.