Quinuclidine


Quinuclidine is an organic compound and a bicyclic amine and used as a catalyst and a chemical building block. It is a strong base with pKa of the conjugate acid of 11.0. It can be prepared by reduction of quinuclidone.
In alkane solvents quinuclidine is a Lewis base that forms adducts with a variety of Lewis acids. It is classified as a soft base and its acceptor properties are discussed in the ECW model.
The compound is structurally related to DABCO, in which the other bridgehead is also nitrogen, and to tropane, which has a slightly different carbon frame.
Quinuclidine is found as a structural component of some biomolecules including quinine.