RGS7


Regulator of G-protein signaling 7 is a protein that in humans is encoded by the RGS7 gene.
RGS7 is highly enriched in the brain where it acts as a universal inhibitor of Gi/o-coupled GPCR. RGS7 is a GTPase-activating protein. It accelerates the GTP hydrolysis on G proteins determining their fast inactivation and acting as intracellular antagonists of GPCR signaling.

Interactions

RGS7 has been shown to interact with: