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RNR3
RNA, ribosomal
3
, also known as
RNR3
, is a
human gene
. It is
a minor
isoform
of
large subunit
of
ribonucleotide-diphosphate reductase
; the
RNR complex
catalyzes
rate-limiting step
in
dNTP
synthesis,
regulated
by
DNA replication
and
DNA damage checkpoint
pathways
via localization of small
subunits
; RNR3 has a
paralog
,
RNR1
, that
arose
from the
whole genome duplication
.