After strong performances in the 1968 Australian Championships and Olympic trials, Boyle was selected to represent Australia at the 1968 Summer Olympics in Mexico City, at the age of 16. At 17, she won a silver medal in the 200-metre sprint and placed 4th in the 100 metres. Setting world junior records in both distances, of 22.73 and 11.20 seconds. The 200-metre record lasted 12 years before being broken; the 100-metre 8 years. Boyle competed in the 1970 British Commonwealth Games in Edinburgh, where she contributed to Australia's number one position on the medal tally with three gold medals, in the 100 and 200-metre sprints and the 4 × 100-metre relay. At the 1972 Olympics in Munich, Boyle collected two more silver medals, in the 100-metre and 200-metre sprints. In both races, she came second to East German Renate Stecher. In 1974, at the ChristchurchBritish Commonwealth Games, Boyle duplicated her results at the Edinburgh Games, winning three more gold medals in the same three events. Breaking the games record in the both 100 metres 11.27 and 200 metres with a 22.50 clocking. In January 1976, she and her team-mates beat an eight year old world record for the 4 × 100 metre relay in Brisbane. At the 1976 Olympics in Montreal, Boyle finished fourth in the final of the 100-metre sprint, but was disqualified from the 200-metre-race for making two false starts. A video replay later showed that she had not false started on her first start. However, Boyle did receive the honour of acting as the flag bearer for the Australian team, the first woman to do so. Boyle was unable to replicate her previous Commonwealth success at the 1978 Commonwealth Games in Edmonton, winning only a silver medal in the 100-metre sprint before withdrawing from the 200m and relay due to injury. Boyle was selected to compete in the 1980 Olympics in Moscow but eventually withdrew from the team for what she stated were personal reasons, during the long dispute within Australian sporting circles over whether to join the USA led boycott of the Games. Her final major competitive appearance was at the 1982 Commonwealth Games in Brisbane, where she won gold in the 400-metre sprint, and silver in the 4 × 400-metre relay. Through her successful career, Boyle won seven gold and two silver medals at the Commonwealth Games, in addition to her three silver medals at the Olympic Games. It is widely considered that Boyle was deprived of Olympic gold as many East German athletes were later revealed to have used anabolic steroids within a systematic state-sponsored doping program. The IOC only banned the use of anabolic steroids in 1975.
2007 - appointed as a Member of the Order of Australia for service to the community through a range of roles with organisations that support people with cancer, particularly Breast Cancer Network Australia.
2013 - named in Australia's Top 100 Sportswomen of All Time.
Boyle was diagnosed with cancer in 1996 and ovarian cancer in 2000 and 2001. Boyle works to raise community awareness about breast cancer and has been a very active board member of Breast Cancer Network Australia since 1999. Boyle currently lives on the Sunshine Coast in Queensland with her partner Judy Wild.